Version 5.4
Homo sapiens Gene: TMCO1
Summary
InnateDB Gene IDBG-104489.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMCO1
Gene Name transmembrane and coiled-coil domains 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000143183
Encoded Proteins
IDBP-104491
transmembrane and coiled-coil domains 1
IDBP-246285
transmembrane and coiled-coil domains 1
IDBP-722168
IDBP-721539
IDBP-721938
IDBP-722249
IDBP-722045
IDBP-809562
transmembrane and coiled-coil domains 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This locus encodes a transmembrane protein. Mutations at this locus have been associated with craniofacial dysmorphism, skeletal anomalies, and mental retardation. Mutations at this locus have also been associated with open angle glaucoma blindness. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:165724293-165827755
Strand Reverse strand
Band q24.1
Transcripts
ENST00000367881 ENSP00000356856
ENST00000392129 ENSP00000375975
ENST00000464650 ENSP00000463951
ENST00000476143 ENSP00000464127
ENST00000481278 ENSP00000462300
ENST00000465705 ENSP00000463105
ENST00000580248 ENSP00000462588
ENST00000612311 ENSP00000480514
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0000139 Golgi membrane
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000052428
View Gene Order
ENSBTAG00000010009
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.31498 Hs.93832
RefSeq NM_001256164 NM_001256165 NM_019026
HUGO
OMIM
CCDS CCDS1251
HPRD 14243
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca