Version 5.4
Homo sapiens Gene: MAEL
Summary
InnateDB Gene IDBG-104521.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAEL
Gene Name maelstrom homolog (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000143194
Encoded Proteins
IDBP-104523
maelstrom homolog (Drosophila)
IDBP-104525
maelstrom homolog (Drosophila)
IDBP-389471
maelstrom homolog (Drosophila)
IDBP-813360
maelstrom spermatogenic transposon silencer
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:166975582-167022214
Strand Forward strand
Band q24.1
Transcripts
ENST00000367872 ENSP00000356846
ENST00000367870 ENSP00000356844
ENST00000447624 ENSP00000402143
ENST00000491055
ENST00000487826
ENST00000622874 ENSP00000482771
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0000902 cell morphogenesis
GO:0006974 cellular response to DNA damage stimulus
GO:0007129 synapsis
GO:0007140 male meiosis
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0009566 fertilization
GO:0010629 negative regulation of gene expression
GO:0030154 cell differentiation
GO:0031047 gene silencing by RNA
GO:0034587 piRNA metabolic process
GO:0043046 DNA methylation involved in gamete generation
GO:0043066 negative regulation of apoptotic process
GO:0046620 regulation of organ growth
Cellular Component
GO:0000785 chromatin
GO:0001741 XY body
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0030849 autosome
GO:0033391 chromatoid body
GO:0043186 P granule
GO:0048471 perinuclear region of cytoplasm
GO:0071547 piP-body
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000040629
View Gene Order
ENSBTAG00000016550
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.651245
RefSeq NM_001286377 NM_001286378 NM_032858 XM_006711582 XM_006711583
HUGO
OMIM
CCDS CCDS1257 CCDS65712 CCDS72975
HPRD 08609
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca