Version 5.4
Homo sapiens Gene: MR1
Summary
InnateDB Gene IDBG-105193.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MR1
Gene Name major histocompatibility complex, class I-related
Synonyms HLALS
Species Homo sapiens
Ensembl Gene ENSG00000153029
Encoded Proteins
IDBP-105195
major histocompatibility complex, class I-related
IDBP-105197
major histocompatibility complex, class I-related
IDBP-105199
major histocompatibility complex, class I-related
IDBP-389785
major histocompatibility complex, class I-related
IDBP-811715
major histocompatibility complex, class I-related
IDBP-811716
major histocompatibility complex, class I-related
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:181033425-181061938
Strand Forward strand
Band q25.3
Transcripts
ENST00000367580 ENSP00000356552
ENST00000282990 ENSP00000282990
ENST00000367579 ENSP00000356551
ENST00000367578
ENST00000438435
ENST00000434571 ENSP00000388504
ENST00000486453
ENST00000617803 ENSP00000478976
ENST00000614012 ENSP00000477563
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0032393 MHC class I receptor activity
GO:0042605 peptide antigen binding
Biological Process
GO:0001916 positive regulation of T cell mediated cytotoxicity
GO:0002367 cytokine production involved in immune response
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0006955 immune response
GO:0007165 signal transduction
GO:0019882 antigen processing and presentation
GO:0032611 interleukin-1 beta production
GO:0032620 interleukin-17 production
GO:0045087 innate immune response
GO:0050829 defense response to Gram-negative bacterium
Cellular Component
GO:0005576 extracellular region
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
GO:0042612 MHC class I protein complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026471
View Gene Order
ENSBTAG00000009924
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001194999 NM_001195000 NM_001195035 NM_001531 XM_005245115
HUGO
OMIM
CCDS CCDS1342 CCDS53440 CCDS53441 CCDS53442
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca