Version 5.4
Homo sapiens Gene: SQRDL
Summary
InnateDB Gene IDBG-10538.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SQRDL
Gene Name sulfide quinone reductase-like (yeast)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000137767
Encoded Proteins
IDBP-10540
sulfide quinone reductase-like (yeast)
IDBP-747004
IDBP-747613
IDBP-744930
IDBP-745808
IDBP-746803
IDBP-745089
IDBP-744772
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene may function in mitochondria to catalyze the conversion of sulfide to persulfides, thereby decreasing toxic concencrations of sulfide. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:45631148-45691294
Strand Forward strand
Band q21.1
Transcripts
ENST00000260324 ENSP00000260324
ENST00000561493 ENSP00000457937
ENST00000566934 ENSP00000454520
ENST00000561735 ENSP00000456075
ENST00000565227 ENSP00000457592
ENST00000568606 ENSP00000456019
ENST00000565997 ENSP00000454953
ENST00000563296 ENSP00000456979
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 13 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016491 oxidoreductase activity
GO:0070224 sulfide:quinone oxidoreductase activity
Biological Process
GO:0000096 sulfur amino acid metabolic process
GO:0000098 sulfur amino acid catabolic process
GO:0034641 cellular nitrogen compound metabolic process
GO:0044281 small molecule metabolic process
GO:0055114 oxidation-reduction process
GO:0070221 sulfide oxidation, using sulfide:quinone oxidoreductase
Cellular Component
GO:0005743 mitochondrial inner membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000005803
View Gene Order
ENSBTAG00000010365
Not yet available
Pathways
NETPATH
REACTOME
REACT_116010
Sulfide oxidation to sulfate pathway
REACT_115654
Degradation of cysteine and homocysteine pathway
REACT_115639
Sulfur amino acid metabolism pathway
REACT_13
Metabolism of amino acids and derivatives pathway
REACT_111217
Metabolism pathway
KEGG
hsa00920
Sulfur metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.511251
RefSeq NM_001271213 NM_021199
HUGO
OMIM
CCDS CCDS10127
HPRD 18102
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca