Homo sapiens Gene: KIF21B
Summary
InnateDB Gene IDBG-105683.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KIF21B
Gene Name kinesin family member 21B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000116852
Encoded Proteins
kinesin family member 21B
kinesin family member 21B
kinesin family member 21B
kinesin family member 21B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the kinesin superfamily. Kinesins are ATP-dependent microtubule-based motor proteins that are involved in the intracellular transport of membranous organelles. Single nucleotide polymorphisms in this gene are associated with inflammatory bowel disease and multiple sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:200969390-201023700
Strand Reverse strand
Band q32.1
Transcripts
ENST00000360529 ENSP00000353724
ENST00000332129 ENSP00000328494
ENST00000422435 ENSP00000411831
ENST00000461742 ENSP00000433808
ENST00000534043
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003777 microtubule motor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005871 kinesin complex
GO:0005874 microtubule
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt O75037
TrEMBL
UniProt Splice Variant
Entrez Gene 23046
UniGene
RefSeq NM_001252102 NM_001252103 NM_017596 NM_001252100
HUGO HGNC:29442
OMIM 608322
CCDS CCDS58055 CCDS58054 CCDS30965 CCDS58056
HPRD
IMGT
EMBL AB007918 AC099756 AL358473 BC137281 BC144557 CH471067
GenPept AAI37282 AAI44558 BAA32294 EAW91328
RNA Seq Atlas 23046