Version 5.4
Homo sapiens Gene: SOX13
Summary
InnateDB Gene IDBG-106002.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SOX13
Gene Name SRY (sex determining region Y)-box 13
Synonyms ICA12; Sox-13
Species Homo sapiens
Ensembl Gene ENSG00000143842
Encoded Proteins
IDBP-106006
SRY (sex determining region Y)-box 13
IDBP-595739
SRY (sex determining region Y)-box 13
IDBP-598325
SRY (sex determining region Y)-box 13
IDBP-590517
SRY (sex determining region Y)-box 13
IDBP-806675
SRY (sex determining region Y)-box 13
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. It has also been determined to be a type-1 diabetes autoantigen, also known as islet cell antibody 12. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:204073115-204127743
Strand Forward strand
Band q32.1
Transcripts
ENST00000367204 ENSP00000356172
ENST00000272193
ENST00000367203
ENST00000480326 ENSP00000434093
ENST00000534185
ENST00000530882
ENST00000525442 ENSP00000433595
ENST00000528591 ENSP00000436297
ENST00000525258
ENST00000618875 ENSP00000478239
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0009653 anatomical structure morphogenesis
GO:0045586 regulation of gamma-delta T cell differentiation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000070643
View Gene Order
ENSBTAG00000008132
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.201671
RefSeq NM_005686 XM_005245623
HUGO
OMIM
CCDS CCDS44299
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca