Homo sapiens Gene: DSTYK
Summary
InnateDB Gene IDBG-106106.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DSTYK
Gene Name dual serine/threonine and tyrosine protein kinase
Synonyms CAKUT1; DustyPK; RIP5; RIPK5;
Species Homo sapiens
Ensembl Gene ENSG00000133059
Encoded Proteins
dual serine/threonine and tyrosine protein kinase
dual serine/threonine and tyrosine protein kinase
dual serine/threonine and tyrosine protein kinase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a dual serine/threonine and tyrosine protein kinase which is expressed in multiple tissues. It is thought to function as a regulator of cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:205142505-205211566
Strand Reverse strand
Band q32.1
Transcripts
ENST00000367162 ENSP00000356130
ENST00000367161 ENSP00000356129
ENST00000615388 ENSP00000478016
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004712 protein serine/threonine/tyrosine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0018108 peptidyl-tyrosine phosphorylation
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 25778
UniGene
RefSeq NM_015375 NM_199462
HUGO HGNC:29043
OMIM 612666
CCDS CCDS1451 CCDS1452
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 25778