Version 5.4
Homo sapiens Gene: DSTYK
Summary
InnateDB Gene IDBG-106106.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DSTYK
Gene Name dual serine/threonine and tyrosine protein kinase
Synonyms CAKUT1; DustyPK; RIP5; RIPK5
Species Homo sapiens
Ensembl Gene ENSG00000133059
Encoded Proteins
IDBP-106108
dual serine/threonine and tyrosine protein kinase
IDBP-106110
dual serine/threonine and tyrosine protein kinase
IDBP-808940
dual serine/threonine and tyrosine protein kinase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a dual serine/threonine and tyrosine protein kinase which is expressed in multiple tissues. It is thought to function as a regulator of cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:205142505-205211566
Strand Reverse strand
Band q32.1
Transcripts
ENST00000367162 ENSP00000356130
ENST00000367161 ENSP00000356129
ENST00000615388 ENSP00000478016
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004712 protein serine/threonine/tyrosine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0018108 peptidyl-tyrosine phosphorylation
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000042046
View Gene Order
ENSBTAG00000016618
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 25778
UniGene
RefSeq NM_015375 NM_199462
HUGO HGNC:29043
OMIM 612666
CCDS CCDS1451 CCDS1452
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 25778

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca