Homo sapiens Gene: DTL
Summary
InnateDB Gene IDBG-106535.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DTL
Gene Name denticleless E3 ubiquitin protein ligase homolog (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000143476
Encoded Proteins
denticleless homolog (Drosophila)
denticleless homolog (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:212035553-212107400
Strand Forward strand
Band q32.3
Transcripts
ENST00000366991 ENSP00000355958
ENST00000475419
ENST00000489149
ENST00000463791
ENST00000496442
ENST00000542077 ENSP00000443870
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 55 experimentally validated interaction(s) in this database.
Experimentally validated
Total 55 [view]
Protein-Protein 53 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
Biological Process
GO:0000209 protein polyubiquitination
GO:0006260 DNA replication
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006513 protein monoubiquitination
GO:0006974 cellular response to DNA damage stimulus
GO:0009411 response to UV
GO:0019985 translesion synthesis
GO:0031572 G2 DNA damage checkpoint
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0031464 Cul4A-RING E3 ubiquitin ligase complex
GO:0031465 Cul4B-RING E3 ubiquitin ligase complex
GO:0031965 nuclear membrane
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q9NZJ0
TrEMBL
UniProt Splice Variant
Entrez Gene 51514
UniGene Hs.606773 Hs.656473
RefSeq NM_016448 NM_001286229 NM_001286230
HUGO HGNC:30288
OMIM 610617
CCDS CCDS1502 CCDS65778
HPRD 17952
IMGT
EMBL AC092814 AF195765 AF345896 AK000742 AK001206 AK001261 AK027651 AK292343 AL592297 AL606468 BC033297 BC033540 CH471100 DQ641253
GenPept AAF35182 AAH33297 AAH33540 AAK54706 ABG23317 BAA91355 BAA91552 BAA91586 BAB55267 BAF85032 CAH70697 CAH73803 EAW93395 EAW93397
RNA Seq Atlas 51514