Version 5.4
Homo sapiens Gene: ENAH
Summary
InnateDB Gene IDBG-106949.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ENAH
Gene Name enabled homolog (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000154380
Encoded Proteins
IDBP-106951
enabled homolog (Drosophila)
IDBP-106953
enabled homolog (Drosophila)
IDBP-106957
enabled homolog (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:225486835-225653142
Strand Reverse strand
Band q42.12
Transcripts
ENST00000366844 ENSP00000355809
ENST00000366843 ENSP00000355808
ENST00000358675
ENST00000284563 ENSP00000284563
ENST00000391874
ENST00000498108
ENST00000483952
ENST00000497899
ENST00000612656
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 30 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 30 [view]
Protein-Protein 29 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0017124 SH3 domain binding
GO:0050699 WW domain binding
Biological Process
GO:0001843 neural tube closure
GO:0007411 axon guidance
GO:0008154 actin polymerization or depolymerization
GO:0030036 actin cytoskeleton organization
GO:0046907 intracellular transport
GO:0050852 T cell receptor signaling pathway
Cellular Component
GO:0001725 stress fiber
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0030027 lamellipodium
GO:0030054 cell junction
GO:0030175 filopodium
GO:0045202 synapse
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022995
View Gene Order
ENSBTAG00000016185
Not yet available
Pathways
NETPATH
NetPath_11
TCR pathway
REACTOME
REACT_12623
Generation of second messenger molecules pathway
REACT_19351
Signaling by Robo receptor pathway
REACT_111045
Developmental Biology pathway
REACT_12526
TCR signaling pathway
REACT_18266
Axon guidance pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
KEGG
hsa04810
Regulation of actin cytoskeleton pathway
INOH
PID NCI
ecadherin_nascentaj_pathway
E-cadherin signaling in the nascent adherens junction
cdc42_pathway
CDC42 signaling events
ecadherin_stabilization_pathway
Stabilization and expansion of the E-cadherin adherens junction
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.497893 Hs.707594 Hs.708428
RefSeq NM_001008493 NM_018212 XM_005273187
HUGO
OMIM
CCDS CCDS31040 CCDS31041
HPRD 12360
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca