Version 5.4
Homo sapiens Gene: EXOC8
Summary
InnateDB Gene IDBG-107417.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EXOC8
Gene Name exocyst complex component 8
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000116903
Encoded Proteins
IDBP-107419
exocyst complex component 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:231332753-231337852
Strand Reverse strand
Band q42.2
Transcripts
ENST00000366645 ENSP00000355605
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 43 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 43 [view]
Protein-Protein 42 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006887 exocytosis
GO:0015031 protein transport
GO:0034613 cellular protein localization
GO:0044267 cellular protein metabolic process
GO:0061024 membrane organization
Cellular Component
GO:0000145 exocyst
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0030426 growth cone
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
ENSMUSG00000074030
View Gene Order
Ortholuge
SSD Ortholog
Ortholog supports species divergence
ENSBTAG00000006111
Not yet available
Ortholuge
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
REACT_17015
Metabolism of proteins pathway
REACT_147867
Translocation of GLUT4 to the plasma membrane pathway
REACT_15550
Insulin processing pathway
REACT_160078
Peptide hormone metabolism pathway
REACT_11123
Membrane Trafficking pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q8IYI6
TrEMBL
UniProt Splice Variant
Entrez Gene 149371
UniGene Hs.356198 Hs.602432
RefSeq NM_175876
HUGO HGNC:24659
OMIM 615283
CCDS CCDS1593
HPRD
IMGT
EMBL AK096460 AL117352 BC035763 CH471098
GenPept AAH35763 BAG53295 CAI23095 EAW69955
RNA Seq Atlas 149371

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca