Version 5.4
Homo sapiens Gene: ERO1LB
Summary
InnateDB Gene IDBG-107589.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ERO1LB
Gene Name ERO1-like beta (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000086619
Encoded Proteins
IDBP-107591
ERO1-like beta (S. cerevisiae)
IDBP-107593
ERO1-like beta (S. cerevisiae)
IDBP-107597
ERO1-like beta (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:236215555-236281985
Strand Reverse strand
Band q42.3
Transcripts
ENST00000354619 ENSP00000346635
ENST00000264181 ENSP00000264181
ENST00000366589 ENSP00000355548
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003756 protein disulfide isomerase activity
GO:0005515 protein binding
GO:0015035 protein disulfide oxidoreductase activity
GO:0016491 oxidoreductase activity
GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
GO:0051082 unfolded protein binding
Biological Process
GO:0006457 protein folding
GO:0019471 4-hydroxyproline metabolic process
GO:0022417 protein maturation by protein folding
GO:0030070 insulin processing
GO:0030198 extracellular matrix organization
GO:0042593 glucose homeostasis
GO:0045454 cell redox homeostasis
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000057069
View Gene Order
ENSBTAG00000034633
Not yet available
Pathways
NETPATH
REACTOME
REACT_15550
Insulin processing pathway
REACT_17015
Metabolism of proteins pathway
REACT_160078
Peptide hormone metabolism pathway
KEGG
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt Q86YB8
TrEMBL Q5T1H5 Q5TAE8
UniProt Splice Variant
Entrez Gene 56605
UniGene Hs.558519 Hs.678123 Hs.736207 Hs.738992
RefSeq NM_019891
HUGO HGNC:14355
OMIM 615437
CCDS CCDS31064
HPRD
IMGT
EMBL AF252538 AL139162 AL450309 BC032823 BC044573
GenPept AAF97547 AAH32823 AAH44573 CAI14420 CAI23525
RNA Seq Atlas 56605

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca