InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: SIPA1L1

Summary

InnateDB Gene

IDBG-10948.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SIPA1L1

Gene Name

signal-induced proliferation-associated 1 like 1

Synonyms

E6TP1

Species

Homo sapiens

Ensembl Gene

ENSG00000197555

Encoded Proteins

IDBP-10950

signal-induced proliferation-associated 1 like 1

IDBP-10952

signal-induced proliferation-associated 1 like 1

IDBP-587037

signal-induced proliferation-associated 1 like 1

IDBP-602485

signal-induced proliferation-associated 1 like 1

IDBP-601362

signal-induced proliferation-associated 1 like 1

IDBP-592456

signal-induced proliferation-associated 1 like 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 14:71320449-71741229

Strand

Forward strand

Band

q24.2

Transcripts

ENST00000358550	ENSP00000351352
ENST00000381232	ENSP00000370630
ENST00000553453
ENST00000555989
ENST00000556408
ENST00000554126
ENST00000556780
ENST00000554362
ENST00000555652
ENST00000557151	ENSP00000452080
ENST00000557469
ENST00000557712
ENST00000555818	ENSP00000450832
ENST00000537413	ENSP00000440682
ENST00000555066	ENSP00000452450
ENST00000554960
ENST00000554874
ENST00000556959

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	16 [view]
Protein-Protein	16 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005096	GTPase activator activity
GO:0005515	protein binding
GO:0046875	ephrin receptor binding

Biological Process

GO:0008150	biological_process
GO:0031532	actin cytoskeleton reorganization
GO:0032317	regulation of Rap GTPase activity
GO:0032861	activation of Rap GTPase activity
GO:0043547	positive regulation of GTPase activity
GO:0048013	ephrin receptor signaling pathway
GO:0048167	regulation of synaptic plasticity
GO:0050770	regulation of axonogenesis
GO:0051056	regulation of small GTPase mediated signal transduction
GO:0061001	regulation of dendritic spine morphogenesis

Cellular Component

GO:0005575	cellular_component
GO:0005737	cytoplasm
GO:0014069	postsynaptic density
GO:0030054	cell junction
GO:0043197	dendritic spine
GO:0045211	postsynaptic membrane

Orthologs

Species

Mus musculus

Bos taurus

Gene ID

Gene Order

ENSMUSG00000042700

View Gene Order

ENSBTAG00000015805

Not yet available

Cross-References

SwissProt

TrEMBL

H0YJY2

UniProt Splice Variant

Entrez Gene

26037

UniGene

Hs.605381 Hs.654657 Hs.736869

RefSeq

NM_001284245 NM_001284246 NM_001284247 NM_015556 XM_005267514 XM_005267516 XM_005267519 XM_006720109 XM_006720110 XM_006720111 XM_006720112

HUGO

HGNC:20284

OMIM

CCDS

CCDS61490 CCDS61491 CCDS9807

HPRD

11559

IMGT

EMBL

AC004900 AC004968 AC004974 AC005476 AC005994 AL391735

GenPept

RNA Seq Atlas

26037