Version 5.4
Homo sapiens Gene: ACOT2
Summary
InnateDB Gene IDBG-11569.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACOT2
Gene Name acyl-CoA thioesterase 2
Synonyms CTE-IA; CTE1A; MTE1; PTE2; PTE2A; ZAP128
Species Homo sapiens
Ensembl Gene ENSG00000119673
Encoded Proteins
IDBP-11571
acyl-CoA thioesterase 2
IDBP-602665
acyl-CoA thioesterase 2
IDBP-812071
acyl-CoA thioesterase 2
IDBP-812073
acyl-CoA thioesterase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the acyl-CoA thioesterase protein family, and is one of four acyl-CoA hydrolase genes located in a cluster on chromosome 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:73567620-73575658
Strand Forward strand
Band q24.3
Transcripts
ENST00000238651 ENSP00000238651
ENST00000538782 ENSP00000440961
ENST00000557857
ENST00000613168 ENSP00000477685
ENST00000622407 ENSP00000483704
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0016290 palmitoyl-CoA hydrolase activity
GO:0016790 thiolester hydrolase activity
GO:0047617 acyl-CoA hydrolase activity
Biological Process
GO:0000038 very long-chain fatty acid metabolic process
GO:0001676 long-chain fatty acid metabolic process
GO:0006637 acyl-CoA metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
hsa01040
Biosynthesis of unsaturated fatty acids pathway
hsa00062
Fatty acid elongation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 10965
UniGene Hs.446685 Hs.699708
RefSeq NM_006821
HUGO HGNC:18431
OMIM 609972
CCDS CCDS9816
HPRD 10173
IMGT
EMBL
GenPept
RNA Seq Atlas 10965

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca