Version 5.4
Homo sapiens Gene: ACYP1
Summary
InnateDB Gene IDBG-12798.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACYP1
Gene Name acylphosphatase 1, erythrocyte (common) type
Synonyms ACYPE
Species Homo sapiens
Ensembl Gene ENSG00000119640
Encoded Proteins
IDBP-12800
acylphosphatase 1, erythrocyte (common) type
IDBP-12802
acylphosphatase 1, erythrocyte (common) type
IDBP-591781
acylphosphatase 1, erythrocyte (common) type
IDBP-601815
acylphosphatase 1, erythrocyte (common) type
IDBP-596305
acylphosphatase 1, erythrocyte (common) type
IDBP-583144
acylphosphatase 1, erythrocyte (common) type
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Acylphosphatase is a small cytosolic enzyme that catalyzes the hydrolysis of the carboxyl-phosphate bond of acylphosphates. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase, on the basis of their tissue localization. This gene encodes the erythrocyte acylphosphatase isoenzyme. Alternatively spliced transcript variants that encode different proteins were identified through data analysis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:75053221-75069483
Strand Reverse strand
Band q24.3
Transcripts
ENST00000238618 ENSP00000238618
ENST00000357971 ENSP00000350655
ENST00000555463 ENSP00000450873
ENST00000555694 ENSP00000451581
ENST00000555135 ENSP00000452249
ENST00000553302 ENSP00000451220
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003998 acylphosphatase activity
Biological Process
GO:0006796 phosphate-containing compound metabolic process
GO:0008152 metabolic process
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000008822
View Gene Order
ENSBTAG00000013992
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00620
Pyruvate metabolism pathway
INOH
INOH website
Pyruvate metabolism pathway
PID NCI
Cross-References
SwissProt P07311
TrEMBL
UniProt Splice Variant
Entrez Gene 97
UniGene
RefSeq NM_001107 NM_203488 XM_005268239 XM_005268240
HUGO HGNC:179
OMIM 600875
CCDS CCDS9838 CCDS45137
HPRD 02928
IMGT
EMBL AC007055 AK312101 AL049780 BC035568 BG614847 CH471061 X84194
GenPept AAD31937 AAH35568 BAG35037 CAA58987 EAW81216
RNA Seq Atlas 97

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca