Version 5.4
Homo sapiens Gene: BATF
Summary
InnateDB Gene IDBG-13023.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BATF
Gene Name basic leucine zipper transcription factor, ATF-like
Synonyms B-ATF; BATF1; SFA-2; SFA2
Species Homo sapiens
Ensembl Gene ENSG00000156127
Encoded Proteins
IDBP-13025
basic leucine zipper transcription factor, ATF-like
IDBP-603128
basic leucine zipper transcription factor, ATF-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:75522425-75547015
Strand Forward strand
Band q24.3
Transcripts
ENST00000286639 ENSP00000286639
ENST00000555795
ENST00000555504 ENSP00000450486
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 30 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 30 [view]
Protein-Protein 28 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001816 cytokine production
GO:0002320 lymphoid progenitor cell differentiation
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006974 cellular response to DNA damage stimulus
GO:0030330 DNA damage response, signal transduction by p53 class mediator
GO:0042832 defense response to protozoan
GO:0043011 myeloid dendritic cell differentiation
GO:0045064 T-helper 2 cell differentiation
GO:0045190 isotype switching
GO:0060218 hematopoietic stem cell differentiation
GO:0072539 T-helper 17 cell differentiation
GO:0072540 T-helper 17 cell lineage commitment
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034266
View Gene Order
ENSBTAG00000025405
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_006399
HUGO
OMIM
CCDS CCDS9843
HPRD 09820
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca