Mus musculus Gene: Myo10
Summary
InnateDB Gene IDBG-130902.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Myo10
Gene Name myosin X
Synonyms AW048724; D15Ertd600e; mKIAA0799;
Species Mus musculus
Ensembl Gene ENSMUSG00000022272
Encoded Proteins
myosin X
myosin X
myosin X
myosin X
myosin X
myosin X
myosin X
myosin X
myosin X
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000145555:
This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-10 (MYH10). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. This gene functions as an actin-based molecular motor and plays a role in integration of F-actin and microtubule cytoskeletons during meiosis. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:25622525-25813673
Strand Forward strand
Band B1
Transcripts
ENSMUST00000022882 ENSMUSP00000022882
ENSMUST00000110457 ENSMUSP00000106087
ENSMUST00000137601 ENSMUSP00000118280
ENSMUST00000127486
ENSMUST00000130517
ENSMUST00000126076
ENSMUST00000135981 ENSMUSP00000123057
ENSMUST00000135173 ENSMUSP00000118744
ENSMUST00000131834 ENSMUSP00000119200
ENSMUST00000124966 ENSMUSP00000120817
ENSMUST00000151360 ENSMUSP00000119367
ENSMUST00000125667 ENSMUSP00000120566
ENSMUST00000145587
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 5 [view]
Protein-DNA 2 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0030507 spectrin binding
GO:0030898 actin-dependent ATPase activity
GO:0051015 actin filament binding
GO:0060002 plus-end directed microfilament motor activity
Biological Process
GO:0006200 ATP catabolic process
GO:0007165 signal transduction
GO:0008152 metabolic process
GO:0008360 regulation of cell shape
GO:0022409 positive regulation of cell-cell adhesion
GO:0030705 cytoskeleton-dependent intracellular transport
GO:0048870 cell motility
GO:0051489 regulation of filopodium assembly
Cellular Component
GO:0001726 ruffle
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005938 cell cortex
GO:0016459 myosin complex
GO:0030027 lamellipodium
GO:0030175 filopodium
GO:0031527 filopodium membrane
GO:0032433 filopodium tip
GO:0043005 neuron projection
GO:0043025 neuronal cell body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Innate Immune System pathway
Regulation of actin dynamics for phagocytic cup formation pathway
Immune System pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
KEGG
Fc gamma R-mediated phagocytosis pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Regulation of actin dynamics for phagocytic cup formation pathway
Developmental Biology pathway
Innate Immune System pathway
Axon guidance pathway
Netrin-1 signaling pathway
Immune System pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
KEGG
Fc gamma R-mediated phagocytosis pathway
INOH
PID BIOCARTA
PID NCI
Netrin-mediated signaling events
Cross-References
SwissProt
TrEMBL D3YXU7 D3Z2E0 D3Z2P4
UniProt Splice Variant
Entrez Gene 17909
UniGene Mm.60590
RefSeq NM_019472 XM_006520024 XM_006520026
OMIM
CCDS CCDS37049
HPRD
IMGT
MGI ID MGI:107716
MGI Symbol Myo10
EMBL AC115746 AC131178
GenPept
RNA Seq Atlas 17909