InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Rala

Summary

InnateDB Gene

IDBG-132005.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rala

Gene Name

v-ral simian leukemia viral oncogene homolog A (ras related)

Synonyms

3010001O15Rik; AW322615; Ral; Rasl1

Species

Mus musculus

Ensembl Gene

ENSMUSG00000008859

Encoded Proteins

IDBP-132007

v-ral simian leukemia viral oncogene homolog A (ras related)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000006451:
The product of this gene belongs to the small GTPase superfamily, Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. This gene encodes a low molecular mass ras-like GTP-binding protein that shares about 50% similarity with other ras proteins. [provided by RefSeq, Jul 2008]
The product of this gene belongs to the small GTPase superfamily, Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. This gene encodes a low molecular mass ras-like GTP-binding protein that shares about 50%% similarity with other ras proteins. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 13:17880575-17944239

Strand

Reverse strand

Band

Transcripts

ENSMUST00000009003

ENSMUSP00000009003

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 36 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	36 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0031755	Edg-2 lysophosphatidic acid receptor binding

Biological Process

GO:0000910	cytokinesis
GO:0006184	GTP catabolic process
GO:0006886	intracellular protein transport
GO:0006887	exocytosis
GO:0006913	nucleocytoplasmic transport
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0007265	Ras protein signal transduction
GO:0015031	protein transport
GO:0017157	regulation of exocytosis
GO:0031532	actin cytoskeleton reorganization
GO:0051491	positive regulation of filopodium assembly
GO:0051665	membrane raft localization

Cellular Component

GO:0005622	intracellular
GO:0005886	plasma membrane
GO:0009986	cell surface
GO:0016020	membrane
GO:0030139	endocytic vesicle
GO:0030496	midbody
GO:0030659	cytoplasmic vesicle membrane
GO:0032154	cleavage furrow
GO:0070062	extracellular vesicular exosome