InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Usp9x

Summary

InnateDB Gene

IDBG-132506.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Usp9x

Gene Name

ubiquitin specific peptidase 9, X chromosome

Synonyms

5730589N07Rik; AA407302; AA407699; AL022658; AL022749; Dffrx; FAF-X; Fafl

Species

Mus musculus

Ensembl Gene

ENSMUSG00000031010

Encoded Proteins

IDBP-132508

ubiquitin specific peptidase 9, X chromosome

IDBP-622627

ubiquitin specific peptidase 9, X chromosome

IDBP-622630

ubiquitin specific peptidase 9, X chromosome

IDBP-622616

ubiquitin specific peptidase 9, X chromosome

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124486:
This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:13071498-13173328

Strand

Forward strand

Band

A1.1

Transcripts

ENSMUST00000089302	ENSMUSP00000086716
ENSMUST00000149021	ENSMUSP00000133948
ENSMUST00000139764
ENSMUST00000124097
ENSMUST00000133997	ENSMUSP00000134612
ENSMUST00000169594	ENSMUSP00000129373
ENSMUST00000174762

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 95 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	95 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding
GO:0008234	cysteine-type peptidase activity
GO:0036459	ubiquitinyl hydrolase activity
GO:0070410	co-SMAD binding

Biological Process

GO:0001701	in utero embryonic development
GO:0001764	neuron migration
GO:0006511	ubiquitin-dependent protein catabolic process
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0009791	post-embryonic development
GO:0016579	protein deubiquitination
GO:0021698	cerebellar cortex structural organization
GO:0021766	hippocampus development
GO:0030509	BMP signaling pathway
GO:0048675	axon extension
GO:0071560	cellular response to transforming growth factor beta stimulus
GO:1990138	neuron projection extension