Version 5.4
Mus musculus Gene: Wdr33
Summary
InnateDB Gene IDBG-132954.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wdr33
Gene Name WD repeat domain 33
Synonyms 1110001N06Rik; 2310011G05Rik; 2810021O11Rik; 8430413N20Rik; WDC146
Species Mus musculus
Ensembl Gene ENSMUSG00000024400
Encoded Proteins
IDBP-132956
WD repeat domain 33
IDBP-132958
WD repeat domain 33
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136709:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is highly expressed in testis and the protein is localized to the nucleus. This gene may play important roles in the mechanisms of cytodifferentiation and/or DNA recombination. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:31804057-31908987
Strand Forward strand
Band B1
Transcripts
ENSMUST00000082319 ENSMUSP00000080936
ENSMUST00000025264 ENSMUSP00000025264
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 27 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006397 mRNA processing
GO:0008150 biological_process
Cellular Component
GO:0005581 collagen trimer
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000136709
View Gene Order
ENSBTAG00000005987
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03015
mRNA surveillance pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_24
TSLP pathway
REACTOME
KEGG
hsa03015
mRNA surveillance pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q8K4P0
TrEMBL D3YX80 Q8VE87
UniProt Splice Variant
Entrez Gene 74320
UniGene Mm.277705
RefSeq NM_001170967 NM_001170970 NM_028866
OMIM
CCDS CCDS29112 CCDS50242
HPRD
IMGT
MGI ID MGI:1921570
MGI Symbol Wdr33
EMBL AB086191 AC124393 AC131761 AC161511 AK031786 AK050653 BC019526
GenPept AAH19526 BAC00776 BAC27549 BAC34364
RNA Seq Atlas 74320

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca