Mus musculus Gene: Mest
Summary
InnateDB Gene IDBG-133397.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mest
Gene Name mesoderm specific transcript
Synonyms AA408879; AI256745; Peg1;
Species Mus musculus
Ensembl Gene ENSMUSG00000051855
Encoded Proteins
mesoderm specific transcript
mesoderm specific transcript
mesoderm specific transcript
mesoderm specific transcript
mesoderm specific transcript
mesoderm specific transcript
mesoderm specific transcript
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106484:
This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:30723547-30748455
Strand Forward strand
Band A3.3
Transcripts
ENSMUST00000115127 ENSMUSP00000110780
ENSMUST00000141130
ENSMUST00000151777 ENSMUSP00000115541
ENSMUST00000147400 ENSMUSP00000120408
ENSMUST00000157040 ENSMUSP00000119038
ENSMUST00000128398 ENSMUSP00000114679
ENSMUST00000124665 ENSMUSP00000117713
ENSMUST00000131465
ENSMUST00000137521
ENSMUST00000130751
ENSMUST00000149496
ENSMUST00000163949 ENSMUSP00000129639
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
Biological Process
GO:0008152 metabolic process
GO:0010883 regulation of lipid storage
GO:0032526 response to retinoic acid
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL D3Z328
UniProt Splice Variant
Entrez Gene 17294
UniGene
RefSeq NM_001252292 NM_001252293 NM_008590 XM_006505001
OMIM
CCDS CCDS19979
HPRD
IMGT
MGI ID MGI:96968
MGI Symbol Mest
EMBL AC146699 CAAA01093966 CAAA01224227
GenPept
RNA Seq Atlas 17294