Version 5.4
Homo sapiens Gene: WDR18
Summary
InnateDB Gene IDBG-13449.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WDR18
Gene Name WD repeat domain 18
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000065268
Encoded Proteins
IDBP-13451
WD repeat domain 18
IDBP-763097
IDBP-806412
WD repeat domain 18
IDBP-806403
WD repeat domain 18
IDBP-763507
IDBP-761829
IDBP-806413
WD repeat domain 18
IDBP-806411
WD repeat domain 18
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:984271-998438
Strand Forward strand
Band p13.3
Transcripts
ENST00000251289 ENSP00000251289
ENST00000591985 ENSP00000466551
ENST00000591155
ENST00000591997 ENSP00000484670
ENST00000585809 ENSP00000476117
ENST00000591276
ENST00000586317
ENST00000590397 ENSP00000465826
ENST00000587001 ENSP00000464855
ENST00000590354 ENSP00000475953
ENST00000607440 ENSP00000475744
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 49 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 49 [view]
Protein-Protein 49 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007275 multicellular organismal development
Cellular Component
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000035754
View Gene Order
ENSBTAG00000002434
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 57418
UniGene
RefSeq NM_024100
HUGO HGNC:17956
OMIM
CCDS CCDS12051
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 57418

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca