Homo sapiens Gene: CNTN4
Summary
InnateDB Gene IDBG-13493.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CNTN4
Gene Name contactin 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000144619
Encoded Proteins
contactin 4
contactin 4
contactin 4
contactin 4
contactin 4
contactin 4
contactin 4
contactin 4
contactin 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the contactin family of immunoglobulins. Contactins are axon-associated cell adhesion molecules that function in neuronal network formation and plasticity. The encoded protein is a glycosylphosphatidylinositol-anchored neuronal membrane protein that may play a role in the formation of axon connections in the developing nervous system. Deletion or mutation of this gene may play a role in 3p deletion syndrome and autism spectrum disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:2098813-3057956
Strand Forward strand
Band p26.3
Transcripts
ENST00000397461 ENSP00000380602
ENST00000397459 ENSP00000380600
ENST00000422330 ENSP00000408594
ENST00000427741 ENSP00000396719
ENST00000455083 ENSP00000390560
ENST00000418658 ENSP00000396010
ENST00000438282
ENST00000430505
ENST00000434053 ENSP00000404085
ENST00000427331 ENSP00000413642
ENST00000490876
ENST00000480113
ENST00000473058
ENST00000473173
ENST00000473845 ENSP00000422120
ENST00000475817
ENST00000484686
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007158 neuron cell-cell adhesion
GO:0007399 nervous system development
GO:0007409 axonogenesis
GO:0007411 axon guidance
GO:0007413 axonal fasciculation
GO:0007420 brain development
GO:0031175 neuron projection development
GO:0045665 negative regulation of neuron differentiation
GO:0048167 regulation of synaptic plasticity
Cellular Component
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0030424 axon
GO:0031225 anchored component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.298705 Hs.626418 Hs.730404
RefSeq NM_001206955 NM_001206956 NM_175607 NM_175613 XM_006713003 XM_006713004
HUGO
OMIM
CCDS CCDS2558 CCDS43041
HPRD 16239
IMGT
EMBL
GenPept
RNA Seq Atlas