Version 5.4
Mus musculus Gene: Kin
Summary
InnateDB Gene IDBG-135584.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kin
Gene Name antigenic determinant of rec-A protein
Synonyms Kin17
Species Mus musculus
Ensembl Gene ENSMUSG00000037262
Encoded Proteins
IDBP-135586
antigenic determinant of rec-A protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000151657:
The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:10080593-10092806
Strand Forward strand
Band A1
Transcripts
ENSMUST00000042512 ENSMUSP00000043614
ENSMUST00000142599
ENSMUST00000142773
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003690 double-stranded DNA binding
GO:0003723 RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0006397 mRNA processing
GO:0006974 cellular response to DNA damage stimulus
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016363 nuclear matrix
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000151657
View Gene Order
ENSBTAG00000013925
Not yet available
Cross-References
SwissProt Q8K339
TrEMBL
UniProt Splice Variant
Entrez Gene 16588
UniGene
RefSeq NM_025280
OMIM
CCDS CCDS15676
HPRD
IMGT
MGI ID MGI:96676
MGI Symbol Kin
EMBL AK009429 AK167740 AL772367 BC028860 X58472
GenPept AAH28860 BAB26281 BAE39778 CAM13915
RNA Seq Atlas 16588

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca