Version 5.4
Homo sapiens Gene: NGB
Summary
InnateDB Gene IDBG-13630.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NGB
Gene Name neuroglobin
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000165553
Encoded Proteins
IDBP-13632
neuroglobin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an oxygen-binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:77265483-77271312
Strand Reverse strand
Band q24.3
Transcripts
ENST00000298352 ENSP00000298352
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 4 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005344 oxygen transporter activity
GO:0005506 iron ion binding
GO:0019825 oxygen binding
GO:0020037 heme binding
Biological Process
GO:0006915 apoptotic process
GO:0015671 oxygen transport
Cellular Component
GO:0005739 mitochondrion
GO:0043204 perikaryon
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000021032
View Gene Order
ENSBTAG00000016285
Not yet available
Cross-References
SwissProt Q9NPG2
TrEMBL A0M8W9
UniProt Splice Variant
Entrez Gene 58157
UniGene Hs.274363
RefSeq NM_021257
HUGO HGNC:14077
OMIM 605304
CCDS CCDS9856
HPRD 05602
IMGT
EMBL AC007375 AC007954 AF422796 AF422797 AJ245944 AJ245946 AK315395 BC032509 CH471061 DQ008010
GenPept AAF62557 AAF63183 AAH32509 AAL98923 AAL98924 AAY16983 BAG37788 CAC11133 CAC12994 EAW81274
RNA Seq Atlas 58157

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca