Homo sapiens Gene: NGB
Summary
InnateDB Gene IDBG-13630.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NGB
Gene Name neuroglobin
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000165553
Encoded Proteins
neuroglobin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an oxygen-binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:77265483-77271312
Strand Reverse strand
Band q24.3
Transcripts
ENST00000298352 ENSP00000298352
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 4 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005344 oxygen transporter activity
GO:0005506 iron ion binding
GO:0019825 oxygen binding
GO:0020037 heme binding
Biological Process
GO:0006915 apoptotic process
GO:0015671 oxygen transport
Cellular Component
GO:0005739 mitochondrion
GO:0043204 perikaryon
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q9NPG2
TrEMBL A0M8W9
UniProt Splice Variant
Entrez Gene 58157
UniGene Hs.274363
RefSeq NM_021257
HUGO HGNC:14077
OMIM 605304
CCDS CCDS9856
HPRD
IMGT
EMBL AC007375 AC007954 AF422796 AF422797 AJ245944 AJ245946 AK315395 BC032509 CH471061 DQ008010
GenPept AAF62557 AAF63183 AAH32509 AAL98923 AAL98924 AAY16983 BAG37788 CAC11133 CAC12994 EAW81274
RNA Seq Atlas 58157