Version 5.4
Mus musculus Gene: Matr3
Summary
InnateDB Gene IDBG-136841.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Matr3
Gene Name matrin 3
Synonyms 1110061A14Rik; 2810017I02Rik; AI841759; AW555618; D030046F20Rik; mKIAA0723
Species Mus musculus
Ensembl Gene ENSMUSG00000037236
Encoded Proteins
IDBP-621920
matrin 3
IDBP-789229
matrin 3
IDBP-789234
matrin 3
IDBP-789237
matrin 3
IDBP-789239
matrin 3
IDBP-789240
matrin 3
IDBP-789241
matrin 3
IDBP-789242
matrin 3
IDBP-789244
matrin 3
IDBP-789245
matrin 3
IDBP-789246
matrin 3
IDBP-789249
matrin 3
IDBP-789250
matrin 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000015479:
This locus encodes a nuclear matrix protein. Mutations at this locus have been associated with distal myopathy 2, which often includes vocal cord and pharyngeal weakness. Alternatively spliced transcript variants, including read-through transcripts with an upstream locus have been described. Related pseuodgenes have been defined on chr1 and chrX.[provided by RefSeq, Mar 2011]
This gene encodes a nuclear matrix protein, which is proposed to stabilize certain messenger RNA species. Mutations of this gene are associated with distal myopathy 2, which often includes vocal cord and pharyngeal weakness. Alternatively spliced transcript variants, including read-through transcripts composed of the upstream small nucleolar RNA host gene 4 (non-protein coding) and matrin 3 gene sequence, have been identified. Pseudogenes of this gene are located on chromosomes 1 and X. [provided by RefSeq, Aug 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:35562146-35593835
Strand Forward strand
Band B2
Transcripts
ENSMUST00000166793 ENSMUSP00000125761
ENSMUST00000188359 ENSMUSP00000140148
ENSMUST00000187543 ENSMUSP00000140286
ENSMUST00000190653 ENSMUSP00000141135
ENSMUST00000190121 ENSMUSP00000140853
ENSMUST00000188767 ENSMUSP00000141027
ENSMUST00000186796 ENSMUSP00000140128
ENSMUST00000188275 ENSMUSP00000140401
ENSMUST00000187389 ENSMUSP00000139745
ENSMUST00000190029 ENSMUSP00000140846
ENSMUST00000189039 ENSMUSP00000139525
ENSMUST00000186292 ENSMUSP00000139437
ENSMUST00000186614 ENSMUSP00000141189
ENSMUST00000187980
ENSMUST00000186158
ENSMUST00000189019
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 57 interaction(s) predicted by orthology.
Experimentally validated
Total 23 [view]
Protein-Protein 22 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 57 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0008270 zinc ion binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0016363 nuclear matrix
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000015479
View Gene Order
ENSBTAG00000006756
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8K310
TrEMBL Q3TZN1 Q3UFN8 Q5BL18 Q6ZQ61
UniProt Splice Variant
Entrez Gene 17184
UniGene Mm.215034 Mm.466838 Mm.466964 Mm.471883
RefSeq NM_010771
OMIM
CCDS CCDS29142
HPRD
IMGT
MGI ID MGI:1298379
MGI Symbol Matr3
EMBL AK087939 AK129199 AK135937 AK148384 AK157744 BC029070 BC090833 CH466557
GenPept AAH29070 AAH90833 BAC40050 BAC98009 BAE22731 BAE28522 BAE34177 EDK97131
RNA Seq Atlas 17184

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca