Version 5.4
| Mus musculus Gene: Igll1 | |||||||||||||||||||||||
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| Summary | |||||||||||||||||||||||
| InnateDB Gene | IDBG-137475.5 | ||||||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
| Gene Symbol | Igll1 | ||||||||||||||||||||||
| Gene Name | immunoglobulin lambda-like polypeptide 1 | ||||||||||||||||||||||
| Synonyms | BB139905; Igl-5; Igll; Lambda5 | ||||||||||||||||||||||
| Species | Mus musculus | ||||||||||||||||||||||
| Ensembl Gene | ENSMUSG00000075370 | ||||||||||||||||||||||
| Encoded Proteins |
immunoglobulin lambda-like polypeptide 1
immunoglobulin lambda-like polypeptide 1
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000254709:
This gene encodes one of the immunoglobulin lambda-like polypeptides. It is located within the immunoglobulin lambda locus but it does not require somatic rearrangement for expression. The first exon of this gene is unrelated to immunoglobulin variable genes; the second and third exons are the immunoglobulin lambda joining 1 and the immunoglobulin lambda constant 1 gene segments. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
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| Gene Information | |||||||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||||||
| Genomic Location | Chromosome 16:16860671-16863985 | ||||||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||||||
| Band | A3 | ||||||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||||||
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Species
Homo sapiens
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
| NETPATH | |||||||||||||||||||||||
| REACTOME |
Regulation of actin dynamics for phagocytic cup formation pathway
Role of phospholipids in phagocytosis pathway
FCGR activation pathway
Classical antibody-mediated complement activation pathway
Initial triggering of complement pathway
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers pathway
Scavenging of heme from plasma pathway
FCERI mediated NF-kB activation pathway
Role of LAT2/NTAL/LAB on calcium mobilization pathway
Innate Immune System pathway
Fc epsilon receptor (FCERI) signaling pathway
Binding and Uptake of Ligands by Scavenger Receptors pathway
Creation of C4 and C2 activators pathway
Adaptive Immune System pathway
Immune System pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Complement cascade pathway
FCERI mediated Ca+2 mobilization pathway
Signaling by the B Cell Receptor (BCR) pathway
FCERI mediated MAPK activation pathway
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| KEGG | |||||||||||||||||||||||
| INOH |
B cell receptor signaling pathway
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| PID NCI | |||||||||||||||||||||||
| Cross-References | |||||||||||||||||||||||
| SwissProt | P20764 | ||||||||||||||||||||||
| TrEMBL | F7CFU6 | ||||||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||||||
| Entrez Gene | 16136 | ||||||||||||||||||||||
| UniGene | Mm.184441 | ||||||||||||||||||||||
| RefSeq | NM_001190325 | ||||||||||||||||||||||
| OMIM | |||||||||||||||||||||||
| CCDS | CCDS49775 | ||||||||||||||||||||||
| HPRD | |||||||||||||||||||||||
| IMGT | |||||||||||||||||||||||
| MGI ID | MGI:96529 | ||||||||||||||||||||||
| MGI Symbol | Igll1 | ||||||||||||||||||||||
| EMBL | AC166832 AJ852426 M30387 | ||||||||||||||||||||||
| GenPept | CAH68524 | ||||||||||||||||||||||
| RNA Seq Atlas | 16136 | ||||||||||||||||||||||