Version 5.4
Mus musculus Gene: Pfdn1
Summary
InnateDB Gene IDBG-137627.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pfdn1
Gene Name prefoldin 1
Synonyms 2700086I23Rik; AA408327; AU044714
Species Mus musculus
Ensembl Gene ENSMUSG00000024346
Encoded Proteins
IDBP-137629
prefoldin 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113068:
This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:36403679-36454495
Strand Reverse strand
Band B2
Transcripts
ENSMUST00000025204 ENSMUSP00000025204
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 60 interaction(s) predicted by orthology.
Predicted by orthology
Total 60 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0051082 unfolded protein binding
Biological Process
GO:0006457 protein folding
GO:0021537 telencephalon development
GO:0021549 cerebellum development
GO:0030036 actin cytoskeleton organization
GO:0042113 B cell activation
Cellular Component
GO:0005575 cellular_component
GO:0016272 prefoldin complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000113068
View Gene Order
ENSBTAG00000016596
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_16936
Prefoldin mediated transfer of substrate to CCT/TriC pathway
REACT_16952
Protein folding pathway
REACT_17004
Chaperonin-mediated protein folding pathway
REACT_17015
Metabolism of proteins pathway
REACT_17029
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding pathway
REACT_223239
Prefoldin mediated transfer of substrate to CCT/TriC pathway
REACT_203284
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding pathway
REACT_219091
Chaperonin-mediated protein folding pathway
REACT_213782
Metabolism of proteins pathway
REACT_215927
Protein folding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q9CQF7
UniProt Splice Variant
Entrez Gene 67199
UniGene Mm.402674
RefSeq NM_026027
OMIM
CCDS CCDS29152
HPRD
IMGT
MGI ID MGI:1914449
MGI Symbol Pfdn1
EMBL AC130714 AC147220 AK002575 AK003330 AK012575 BC094627 CH466557
GenPept AAH94627 BAB22200 BAB22718 BAB28328 EDK97158
RNA Seq Atlas 67199

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca