Mus musculus Gene: Slc25a5 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-138331.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Slc25a5 | ||||||||||||||||||||||
Gene Name | solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 | ||||||||||||||||||||||
Synonyms | Ant2 | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000016319 | ||||||||||||||||||||||
Encoded Proteins |
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000005022:
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Sep 2009] This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome X:36795651-36798807 | ||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||
Band | A3.3 | ||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
They are also associated with 86 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Integration of energy metabolism pathway
Metabolism pathway
Regulation of insulin secretion pathway
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KEGG |
Calcium signaling pathway pathway
Parkinson's disease pathway
Huntington's disease pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Regulation of insulin secretion pathway
Integration of energy metabolism pathway
Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization pathway
Interactions of Vpr with host cellular proteins pathway
HIV Infection pathway
Metabolism pathway
Host Interactions of HIV factors pathway
Disease pathway
Regulation of insulin secretion pathway
Integration of energy metabolism pathway
Metabolism pathway
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KEGG |
Calcium signaling pathway pathway
Parkinson's disease pathway
Huntington's disease pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | P51881 | ||||||||||||||||||||||
TrEMBL | B0LAB5 Q545A2 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 11740 | ||||||||||||||||||||||
UniGene | Mm.389141 Mm.444954 Mm.486471 | ||||||||||||||||||||||
RefSeq | NM_007451 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS30062 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | MGI:1353496 | ||||||||||||||||||||||
MGI Symbol | Slc25a5 | ||||||||||||||||||||||
EMBL | AF240003 AK003467 AK012751 AK088730 BC004570 BC086756 CH466645 EF437333 U10404 U27316 X70847 | ||||||||||||||||||||||
GenPept | AAA19009 AAC52838 AAF64471 AAH04570 AAH86756 ABS83509 BAB22804 BAB28445 BAC40533 CAA50196 EDL28975 | ||||||||||||||||||||||
RNA Seq Atlas | 11740 | ||||||||||||||||||||||