Version 5.4
| Mus musculus Gene: Icam4 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-138732.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Icam4 | ||||||||
| Gene Name | intercellular adhesion molecule 4, Landsteiner-Wiener blood group | ||||||||
| Synonyms | 1810015M19Rik; Cd242; ICAM-4 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000001014 | ||||||||
| Encoded Proteins |
intercellular adhesion molecule 4, Landsteiner-Wiener blood group
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105371:
This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 9:21029373-21030531 | ||||||||
| Strand | Forward strand | ||||||||
| Band | A3 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
Immune System pathway
Extracellular matrix organization pathway
Integrin cell surface interactions pathway
Adaptive Immune System pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
Integrin cell surface interactions pathway
Extracellular matrix organization pathway
Adaptive Immune System pathway
Immune System pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI |
Beta2 integrin cell surface interactions
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| Cross-References | |||||||||
| SwissProt | Q9ERM2 | ||||||||
| TrEMBL | Q14AB0 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 78369 | ||||||||
| UniGene | |||||||||
| RefSeq | NM_023892 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS22890 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1925619 | ||||||||
| MGI Symbol | Icam4 | ||||||||
| EMBL | AF296282 AF296283 AK019013 BC116909 BC116913 CH466522 | ||||||||
| GenPept | AAG30953 AAI16910 AAI16914 AAM97787 BAB31510 EDL25152 | ||||||||
| RNA Seq Atlas | 78369 | ||||||||