Mus musculus Gene: Pcdhb17
Summary
InnateDB Gene IDBG-140004.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pcdhb17
Gene Name protocadherin beta 17
Synonyms mKIAA1621; Pcdhb16; PcdhbQ
Species Mus musculus
Ensembl Gene ENSMUSG00000046387
Encoded Proteins
protocadherin beta 17
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog null:
This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:37485021-37488289
Strand Forward strand
Band B3
Transcripts
ENSMUST00000053856 ENSMUSP00000055072
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL Q91VD8
UniProt Splice Variant
Entrez Gene 93888
UniGene Mm.475430 Mm.87553
RefSeq NM_053142
OMIM
CCDS CCDS29183
HPRD
IMGT
MGI ID MGI:2136754
MGI Symbol Pcdhb17
EMBL AC020967 AK077255 AY013778 BC017149 CH466528
GenPept AAH17149 AAK26067 BAC36711 EDL10154
RNA Seq Atlas 93888