Mus musculus Gene: Pcdhb22
InnateDB Gene IDBG-140074.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pcdhb22
Gene Name protocadherin beta 22
Synonyms Pcdhb15; PcdhbV
Species Mus musculus
Ensembl Gene ENSMUSG00000073591
Encoded Proteins
protocadherin beta 22
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113248:
This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:37518353-37521419
Strand Forward strand
Band B3
ENSMUST00000097609 ENSMUSP00000095214
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
UniProt Splice Variant
Entrez Gene 93893
UniGene Mm.348054 Mm.490624
RefSeq NM_053147
MGI ID MGI:2136760
MGI Symbol Pcdhb22
EMBL AC020967 AY013784 BC094239 CH466528
GenPept AAH94239 AAK26073 EDL10149
RNA Seq Atlas 93893