Version 5.4
Mus musculus Gene: Sec23a
Summary
InnateDB Gene IDBG-141708.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sec23a
Gene Name SEC23A (S. cerevisiae)
Synonyms Msec23; Sec23r
Species Mus musculus
Ensembl Gene ENSMUSG00000020986
Encoded Proteins
IDBP-141710
SEC23A (S. cerevisiae)
IDBP-625629
SEC23A (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100934:
The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family. It is part of a protein complex and found in the ribosome-free transitional face of the endoplasmic reticulum (ER) and associated vesicles. This protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The encoded protein is suggested to play a role in the ER-Golgi protein trafficking. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:58958383-59012017
Strand Reverse strand
Band C1
Transcripts
ENSMUST00000021375 ENSMUSP00000021375
ENSMUST00000154399
ENSMUST00000134223
ENSMUST00000165134 ENSMUSP00000126011
ENSMUST00000169976
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 48 interaction(s) predicted by orthology.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 48 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006888 ER to Golgi vesicle-mediated transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005789 endoplasmic reticulum membrane
GO:0030127 COPII vesicle coat
GO:0030134 ER to Golgi transport vesicle
GO:0030868 smooth endoplasmic reticulum membrane
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000100934
View Gene Order
ENSBTAG00000003708
Not yet available
Pathways
NETPATH
REACTOME
REACT_205304
COPII (Coat Protein 2) Mediated Vesicle Transport pathway
REACT_236645
Class I MHC mediated antigen processing & presentation pathway
REACT_206143
Transport to the Golgi and subsequent modification pathway
REACT_198968
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
REACT_209837
Membrane Trafficking pathway
REACT_188937
Metabolism pathway
REACT_230745
Immune System pathway
REACT_247926
Metabolism of proteins pathway
REACT_236283
Post-translational protein modification pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_196550
MHC class II antigen presentation pathway
REACT_203486
ER to Golgi Transport pathway
REACT_237472
Asparagine N-linked glycosylation pathway
REACT_229531
Adaptive Immune System pathway
REACT_246972
Antigen Presentation: Folding, assembly and peptide loading of class I MHC pathway
KEGG
mmu04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_75795
Antigen Presentation: Folding, assembly and peptide loading of class I MHC pathway
REACT_121399
MHC class II antigen presentation pathway
REACT_12507
COPII (Coat Protein 2) Mediated Vesicle Transport pathway
REACT_25046
Transport to the Golgi and subsequent modification pathway
REACT_22426
Asparagine N-linked glycosylation pathway
REACT_147797
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_22161
Post-translational protein modification pathway
REACT_11203
ER to Golgi Transport pathway
REACT_17015
Metabolism of proteins pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
REACT_111217
Metabolism pathway
REACT_11123
Membrane Trafficking pathway
REACT_218212
Antigen Presentation: Folding, assembly and peptide loading of class I MHC pathway
REACT_214728
Transport to the Golgi and subsequent modification pathway
REACT_212672
Class I MHC mediated antigen processing & presentation pathway
REACT_213138
Immune System pathway
REACT_223866
Asparagine N-linked glycosylation pathway
REACT_211133
MHC class II antigen presentation pathway
REACT_213782
Metabolism of proteins pathway
REACT_214405
Post-translational protein modification pathway
REACT_219933
Metabolism of lipids and lipoproteins pathway
REACT_225088
ER to Golgi Transport pathway
REACT_219139
Metabolism pathway
REACT_220924
COPII (Coat Protein 2) Mediated Vesicle Transport pathway
REACT_214469
Adaptive Immune System pathway
REACT_208174
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
REACT_213260
Membrane Trafficking pathway
KEGG
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.209207 Mm.490584
RefSeq NM_009147 XM_006515628
OMIM
CCDS CCDS25931
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca