Version 5.4
Mus musculus Gene: Rft1
Summary
InnateDB Gene IDBG-142975.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rft1
Gene Name RFT1 homolog (S. cerevisiae)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000052395
Encoded Proteins
IDBP-142977
RFT1 homolog (S. cerevisiae)
IDBP-532699
RFT1 homolog (S. cerevisiae)
IDBP-533076
RFT1 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163933:
This gene encodes an enzyme which catalyzes the translocation of the Man(5)GlcNAc (2)-PP-Dol intermediate from the cytoplasmic to the luminal side of the endoplasmic reticulum membrane in the pathway for the N-glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type In.[provided by RefSeq, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:30654360-30691317
Strand Forward strand
Band B
Transcripts
ENSMUST00000064230 ENSMUSP00000064153
ENSMUST00000133573
ENSMUST00000143923
ENSMUST00000143534
ENSMUST00000155689 ENSMUSP00000122990
ENSMUST00000131097 ENSMUSP00000120407
ENSMUST00000141379
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005319 lipid transporter activity
Biological Process
GO:0006869 lipid transport
GO:0008643 carbohydrate transport
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000163933
View Gene Order
ENSBTAG00000020973
Not yet available
Pathways
NETPATH
REACTOME
REACT_262413
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
REACT_247926
Metabolism of proteins pathway
REACT_236283
Post-translational protein modification pathway
REACT_237472
Asparagine N-linked glycosylation pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22433
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
REACT_22426
Asparagine N-linked glycosylation pathway
REACT_22161
Post-translational protein modification pathway
REACT_17015
Metabolism of proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.259657
RefSeq NM_177815
OMIM
CCDS CCDS26896
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca