Mus musculus Gene: Khk
Summary
InnateDB Gene IDBG-146635.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Khk
Gene Name ketohexokinase
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000029162
Encoded Proteins
ketohexokinase
ketohexokinase
ketohexokinase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138030:
This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:30921556-30931246
Strand Forward strand
Band B1
Transcripts
ENSMUST00000031053 ENSMUSP00000031053
ENSMUST00000117435 ENSMUSP00000114064
ENSMUST00000123885 ENSMUSP00000114540
ENSMUST00000133121
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004454 ketohexokinase activity
GO:0005524 ATP binding
Biological Process
GO:0006000 fructose metabolic process
GO:0046835 carbohydrate phosphorylation
GO:0070873 regulation of glycogen metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Disease pathway
Metabolism pathway
Fructose catabolism pathway
Glycogen storage diseases pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
KEGG
Fructose and mannose metabolism pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
Fructose catabolism pathway
Metabolism pathway
Disease pathway
Glycogen storage diseases pathway
KEGG
Fructose and mannose metabolism pathway
INOH
Fructose Mannose metabolism pathway
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL E9Q1Q9 Q9CPP1
UniProt Splice Variant
Entrez Gene 16548
UniGene
RefSeq XM_006503747 NM_008439 XM_006503748
OMIM
CCDS CCDS39050
HPRD
IMGT
MGI ID MGI:1096353
MGI Symbol Khk
EMBL AC109606 AK008326 AK008503
GenPept BAB25604 BAB25704
RNA Seq Atlas 16548