Version 5.4
Mus musculus Gene: Stx3
Summary
InnateDB Gene IDBG-147158.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Stx3
Gene Name syntaxin 3
Synonyms Syn-3
Species Mus musculus
Ensembl Gene ENSMUSG00000041488
Encoded Proteins
IDBP-147160
syntaxin 3
IDBP-147162
syntaxin 3
IDBP-147164
syntaxin 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166900:
The gene is a member of the syntaxin family. The encoded protein is targeted to the apical membrane of epithelial cells where it forms clusters and is important in establishing and maintaining polarity necessary for protein trafficking involving vesicle fusion and exocytosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:11775119-11819403
Strand Reverse strand
Band A
Transcripts
ENSMUST00000047698 ENSMUSP00000037317
ENSMUST00000075304 ENSMUSP00000074776
ENSMUST00000069285 ENSMUSP00000069529
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005484 SNAP receptor activity
GO:0005515 protein binding
GO:0050544 arachidonic acid binding
Biological Process
GO:0006836 neurotransmitter transport
GO:0006886 intracellular protein transport
GO:0006887 exocytosis
GO:0016192 vesicle-mediated transport
GO:0031175 neuron projection development
GO:0060291 long-term synaptic potentiation
GO:0061025 membrane fusion
Cellular Component
GO:0005911 cell-cell junction
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0030141 secretory granule
GO:0030425 dendrite
GO:0030426 growth cone
GO:0031201 SNARE complex
GO:0042581 specific granule
GO:0042582 azurophil granule
GO:0043005 neuron projection
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000166900
View Gene Order
ENSBTAG00000012820
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04130
SNARE interactions in vesicular transport pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04130
SNARE interactions in vesicular transport pathway
INOH
PID NCI
Cross-References
SwissProt Q64704
TrEMBL Q3TBP0 Q8R1B7
UniProt Splice Variant
Entrez Gene 20908
UniGene Mm.272264 Mm.408218 Mm.471945
RefSeq NM_001025307 NM_011502 NM_152220
OMIM
CCDS CCDS29611 CCDS29612 CCDS29613
HPRD
IMGT
MGI ID MGI:103077
MGI Symbol Stx3
EMBL AC126036 AC126266 AK171135 BC024844 CH466534 D29797 D29798 D29799 D29800 D38375
GenPept AAH24844 BAA06180 BAA06181 BAA06182 BAA06183 BAA07454 BAE42269 EDL41444
RNA Seq Atlas 20908

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca