Version 5.4
Mus musculus Gene: Arhgap32
Summary
InnateDB Gene IDBG-147282.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Arhgap32
Gene Name Rho GTPase activating protein 32
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000041444
Encoded Proteins
IDBP-623097
Rho GTPase activating protein 32
IDBP-623101
Rho GTPase activating protein 32
IDBP-787672
Rho GTPase activating protein 32
IDBP-787675
Rho GTPase activating protein 32
IDBP-787677
Rho GTPase activating protein 32
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134909:
RICS is a neuron-associated GTPase-activating protein that may regulate dendritic spine morphology and strength by modulating Rho GTPase (see RHOA; MIM 165390) activity (Okabe et al., 2003 [PubMed 12531901]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:32116136-32268446
Strand Forward strand
Band A4
Transcripts
ENSMUST00000174641 ENSMUSP00000133898
ENSMUST00000174314
ENSMUST00000168954 ENSMUSP00000128448
ENSMUST00000174730
ENSMUST00000182310 ENSMUSP00000138636
ENSMUST00000182802 ENSMUSP00000138145
ENSMUST00000183121 ENSMUSP00000138584
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 30 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0005515 protein binding
GO:0035091 phosphatidylinositol binding
Biological Process
GO:0007165 signal transduction
GO:0007266 Rho protein signal transduction
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0000139 Golgi membrane
GO:0005622 intracellular
GO:0005789 endoplasmic reticulum membrane
GO:0005938 cell cortex
GO:0010008 endosome membrane
GO:0014069 postsynaptic density
GO:0015629 actin cytoskeleton
GO:0030054 cell junction
GO:0043197 dendritic spine
GO:0045211 postsynaptic membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000134909
View Gene Order
ENSBTAG00000015905
Not yet available
Pathways
NETPATH
REACTOME
REACT_206918
Signaling by Rho GTPases pathway
REACT_210090
Rho GTPase cycle pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
REACT_11051
Rho GTPase cycle pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_111102
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.409696 Mm.46683 Mm.65353
RefSeq NM_001195632 NM_177379 XM_006510442 XM_006510445 XM_006510446
OMIM
CCDS CCDS22951 CCDS57666
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca