Mus musculus Gene: Mtmr7
Summary
InnateDB Gene IDBG-149970.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mtmr7
Gene Name myotubularin related protein 7
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000039431
Encoded Proteins
myotubularin related protein 7
myotubularin related protein 7
myotubularin related protein 7
myotubularin related protein 7
myotubularin related protein 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000003987:
This gene encodes a member of the myotubularin family of tyrosine/dual-specificity phosphatases. The encoded protein is characterized by four distinct domains that are conserved among all members of the myotubularin family: the glucosyltransferase, Rab-like GTPase activator and myotubularins domain, the Rac-induced recruitment domain, the protein tyrosine phosphatases and dual-specificity phosphatases domain and the suppressor of variegation 3-9, enhancer-of-zeste, and trithorax interaction domain. This protein dephosphorylates the target substrates phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:40551095-40634797
Strand Reverse strand
Band A4
Transcripts
ENSMUST00000048890 ENSMUSP00000043367
ENSMUST00000048898 ENSMUSP00000043851
ENSMUST00000173487 ENSMUSP00000134281
ENSMUST00000174205 ENSMUSP00000134731
ENSMUST00000173957 ENSMUSP00000134020
ENSMUST00000174537
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004725 protein tyrosine phosphatase activity
GO:0005515 protein binding
GO:0016791 phosphatase activity
Biological Process
GO:0016311 dephosphorylation
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0046855 inositol phosphate dephosphorylation
GO:0046856 phosphatidylinositol dephosphorylation
Cellular Component
GO:0005829 cytosol
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Synthesis of PIPs at the late endosome membrane pathway
PI Metabolism pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Phospholipid metabolism pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Metabolism of lipids and lipoproteins pathway
Synthesis of PIPs at the late endosome membrane pathway
PI Metabolism pathway
Phospholipid metabolism pathway
Metabolism pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.294871
RefSeq NM_001040699
OMIM
CCDS CCDS40324
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas