Version 5.4
Mus musculus Gene: Rtn2
Summary
InnateDB Gene IDBG-150051.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rtn2
Gene Name reticulon 2 (Z-band associated protein)
Synonyms MMS10-P; Ms10p; Nspl1; NSPLI
Species Mus musculus
Ensembl Gene ENSMUSG00000030401
Encoded Proteins
IDBP-150053
reticulon 2 (Z-band associated protein)
IDBP-264473
reticulon 2 (Z-band associated protein)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125744:
This gene belongs to the family of reticulon encoding genes. Reticulons are necessary for proper generation of tubular endoplasmic reticulum and likely play a role in intracellular vesicular transport. Alternatively spliced transcript variants encoding different isoforms have been identified. Mutations at this locus have been associated with autosomal dominant spastic paraplegia-12. [provided by RefSeq, Apr 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:19282662-19296164
Strand Forward strand
Band A3
Transcripts
ENSMUST00000032559 ENSMUSP00000032559
ENSMUST00000108468 ENSMUSP00000104108
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0046324 regulation of glucose import
GO:0065002 intracellular protein transmembrane transport
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0014802 terminal cisterna
GO:0016021 integral component of membrane
GO:0030315 T-tubule
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000125744
View Gene Order
ENSBTAG00000008185
Not yet available
Cross-References
SwissProt O70622
TrEMBL Q6IM74 Q6IM75
UniProt Splice Variant
Entrez Gene 20167
UniGene
RefSeq NM_001025364 NM_013648
OMIM
CCDS CCDS20896 CCDS39797
HPRD
IMGT
MGI ID MGI:107612
MGI Symbol Rtn2
EMBL AF038537 AF038538 AF038539 AF093624 AK144271 BC031370 BK001789 BK001790 CH466639
GenPept AAC14906 AAC14907 AAC14908 AAC14909 AAD13195 AAH31370 BAE25806 DAA01962 DAA01963 EDL23135
RNA Seq Atlas 20167

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca