Mus musculus Gene: Vav2 | |||||||||||||||||||||||||
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Summary | |||||||||||||||||||||||||
InnateDB Gene | IDBG-151026.6 | ||||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||||
Gene Symbol | Vav2 | ||||||||||||||||||||||||
Gene Name | vav 2 oncogene | ||||||||||||||||||||||||
Synonyms | 2810040F13Rik; AI847175 | ||||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000009621 | ||||||||||||||||||||||||
Encoded Proteins |
vav 2 oncogene
vav 2 oncogene
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Protein Structure | |||||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160293:
VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] |
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Gene Information | |||||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||||
Genomic Location | Chromosome 2:27262104-27427033 | ||||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||||
Band | A3 | ||||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 63 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||||
REACTOME |
Innate Immune System pathway
Regulation of actin dynamics for phagocytic cup formation pathway
GPCR downstream signaling pathway
Hemostasis pathway
Signaling by GPCR pathway
Signaling by VEGF pathway
NRAGE signals death through JNK pathway
Immune System pathway
Platelet activation, signaling and aggregation pathway
Signaling by Rho GTPases pathway
Cell death signalling via NRAGE, NRIF and NADE pathway
EPH-ephrin mediated repulsion of cells pathway
GPVI-mediated activation cascade pathway
EPH-Ephrin signaling pathway
G alpha (12/13) signalling events pathway
VEGFR2 mediated vascular permeability pathway
VEGFA-VEGFR2 Pathway pathway
Axon guidance pathway
Fc epsilon receptor (FCERI) signaling pathway
FCERI mediated Ca+2 mobilization pathway
Rho GTPase cycle pathway
Signal transduction by L1 pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
L1CAM interactions pathway
Signalling by NGF pathway
Developmental Biology pathway
Signal Transduction pathway
p75 NTR receptor-mediated signalling pathway
FCERI mediated MAPK activation pathway
DAP12 interactions pathway
DAP12 signaling pathway
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KEGG |
T cell receptor signaling pathway pathway
Fc epsilon RI signaling pathway pathway
Natural killer cell mediated cytotoxicity pathway
Regulation of actin cytoskeleton pathway
Leukocyte transendothelial migration pathway
Focal adhesion pathway
B cell receptor signaling pathway pathway
Fc gamma R-mediated phagocytosis pathway
Chemokine signaling pathway pathway
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INOH | |||||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||||
NETPATH |
EGFR1 pathway
TCR pathway
BCR pathway
Prolactin pathway
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REACTOME |
DAP12 signaling pathway
DAP12 interactions pathway
Regulation of actin dynamics for phagocytic cup formation pathway
GPVI-mediated activation cascade pathway
NRAGE signals death through JNK pathway
G alpha (12/13) signalling events pathway
Rho GTPase cycle pathway
Signal transduction by L1 pathway
L1CAM interactions pathway
Developmental Biology pathway
Signalling by NGF pathway
Signaling by Rho GTPases pathway
Signaling by VEGF pathway
Signaling by GPCR pathway
Innate Immune System pathway
Platelet activation, signaling and aggregation pathway
VEGFR2 mediated vascular permeability pathway
Axon guidance pathway
Fc epsilon receptor (FCERI) signaling pathway
p75 NTR receptor-mediated signalling pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Immune System pathway
VEGFA-VEGFR2 Pathway pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Cell death signalling via NRAGE, NRIF and NADE pathway
EPH-ephrin mediated repulsion of cells pathway
EPH-Ephrin signaling pathway
FCERI mediated Ca+2 mobilization pathway
FCERI mediated MAPK activation pathway
Hemostasis pathway
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KEGG |
Regulation of actin cytoskeleton pathway
Fc epsilon RI signaling pathway pathway
Leukocyte transendothelial migration pathway
B cell receptor signaling pathway pathway
Focal adhesion pathway
T cell receptor signaling pathway pathway
Natural killer cell mediated cytotoxicity pathway
Fc gamma R-mediated phagocytosis pathway
Chemokine signaling pathway pathway
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INOH | |||||||||||||||||||||||||
PID NCI |
E-cadherin signaling in the nascent adherens junction
Regulation of RAC1 activity
ErbB1 downstream signaling
Nectin adhesion pathway
EPO signaling pathway
Regulation of RhoA activity
BCR signaling pathway
CDC42 signaling events
Regulation of CDC42 activity
PDGFR-beta signaling pathway
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Cross-References | |||||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||||
UniGene | Mm.179011 Mm.487557 | ||||||||||||||||||||||||
RefSeq | NM_009500 XM_006497854 XM_006497855 XM_006497856 | ||||||||||||||||||||||||
OMIM | |||||||||||||||||||||||||
CCDS | CCDS15827 | ||||||||||||||||||||||||
HPRD | |||||||||||||||||||||||||
IMGT | |||||||||||||||||||||||||
MGI ID | |||||||||||||||||||||||||
MGI Symbol | |||||||||||||||||||||||||
EMBL | |||||||||||||||||||||||||
GenPept | |||||||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||||||