Version 5.4
Mus musculus Gene: Fermt2
Summary
InnateDB Gene IDBG-153344.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fermt2
Gene Name fermitin family homolog 2 (Drosophila)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000037712
Encoded Proteins
IDBP-153346
fermitin family homolog 2 (Drosophila)
IDBP-535392
fermitin family homolog 2 (Drosophila)
IDBP-541696
fermitin family homolog 2 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000073712:
Gene Information
Type Protein coding
Genomic Location Chromosome 14:45458792-45530118
Strand Reverse strand
Band C1
Transcripts
ENSMUST00000045905 ENSMUSP00000044554
ENSMUST00000141424 ENSMUSP00000118214
ENSMUST00000150660 ENSMUSP00000120918
ENSMUST00000149723
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
Biological Process
GO:0007160 cell-matrix adhesion
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007229 integrin-mediated signaling pathway
GO:0008360 regulation of cell shape
GO:0016055 Wnt signaling pathway
GO:0033622 integrin activation
GO:0034446 substrate adhesion-dependent cell spreading
GO:0048041 focal adhesion assembly
GO:0072657 protein localization to membrane
Cellular Component
GO:0001725 stress fiber
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005925 focal adhesion
GO:0005938 cell cortex
GO:0009986 cell surface
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0031258 lamellipodium membrane
GO:0031674 I band
GO:0031941 filamentous actin
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000073712
View Gene Order
ENSBTAG00000014501
Not yet available
Pathways
NETPATH
REACTOME
REACT_243772
Cell-extracellular matrix interactions pathway
REACT_241978
Cell junction organization pathway
REACT_223082
Cell-Cell communication pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_20649
Cell-extracellular matrix interactions pathway
REACT_111155
Cell-Cell communication pathway
REACT_20676
Cell junction organization pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8CIB5
TrEMBL Q3TLE2
UniProt Splice Variant
Entrez Gene 218952
UniGene Mm.210018
RefSeq NM_146054 XM_006518828 XM_006518829
OMIM
CCDS CCDS26977
HPRD
IMGT
MGI ID MGI:2385001
MGI Symbol Fermt2
EMBL AK079588 AK166552 BC033436 BC034168 CH466605
GenPept AAH33436 AAH34168 BAC37692 BAE38850 EDL20699
RNA Seq Atlas 218952

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca