Mus musculus Gene: Senp5 | |||||||||
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Summary | |||||||||
InnateDB Gene | IDBG-153497.6 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | Senp5 | ||||||||
Gene Name | SUMO/sentrin specific peptidase 5 | ||||||||
Synonyms | |||||||||
Species | Mus musculus | ||||||||
Ensembl Gene | ENSMUSG00000022772 | ||||||||
Encoded Proteins |
SUMO/sentrin specific peptidase 5
SUMO/sentrin specific peptidase 5
SUMO/sentrin specific peptidase 5
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Protein Structure | |||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||
Entrez Gene | |||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000119231:
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009] |
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Gene Information | |||||||||
Type | Protein coding | ||||||||
Genomic Location | Chromosome 16:31962506-32003287 | ||||||||
Strand | Reverse strand | ||||||||
Band | B2 | ||||||||
Transcripts |
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Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||
NETPATH | |||||||||
REACTOME |
SUMO is proteolytically processed pathway
SUMOylation pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Processing and activation of SUMO pathway
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KEGG | |||||||||
INOH | |||||||||
PID NCI | |||||||||
Pathway Predictions based on Human Orthology Data | |||||||||
NETPATH | |||||||||
REACTOME |
Post-translational protein modification pathway
Processing and activation of SUMO pathway
Metabolism of proteins pathway
SUMO is proteolytically processed pathway
SUMOylation pathway
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KEGG | |||||||||
INOH | |||||||||
PID NCI | |||||||||
Cross-References | |||||||||
SwissProt | |||||||||
TrEMBL | |||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | |||||||||
UniGene | Mm.152890 | ||||||||
RefSeq | NM_177103 XM_006522238 XM_006522239 | ||||||||
OMIM | |||||||||
CCDS | CCDS28111 | ||||||||
HPRD | |||||||||
IMGT | |||||||||
MGI ID | |||||||||
MGI Symbol | |||||||||
EMBL | |||||||||
GenPept | |||||||||
RNA Seq Atlas | |||||||||