Version 5.4
Mus musculus Gene: Itgb5
Summary
InnateDB Gene IDBG-155751.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Itgb5
Gene Name integrin beta 5
Synonyms [b]-5; [b]5; [b]5A; [b]5B; AA475909; AI874634; beta-5; beta5; ESTM23
Species Mus musculus
Ensembl Gene ENSMUSG00000022817
Encoded Proteins
IDBP-155753
integrin beta 5
IDBP-250523
integrin beta 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000082781:
Gene Information
Type Protein coding
Genomic Location Chromosome 16:33829665-33949153
Strand Forward strand
Band B3
Transcripts
ENSMUST00000069345 ENSMUSP00000069416
ENSMUST00000115028 ENSMUSP00000110680
ENSMUST00000134262
ENSMUST00000148462
ENSMUST00000151930
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 30 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005178 integrin binding
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
GO:0007229 integrin-mediated signaling pathway
GO:0007275 multicellular organismal development
Cellular Component
GO:0005925 focal adhesion
GO:0008305 integrin complex
GO:0016020 membrane
GO:0031252 cell leading edge
GO:0043235 receptor complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000082781
View Gene Order
ENSBTAG00000013755
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04512
ECM-receptor interaction pathway
mmu04810
Regulation of actin cytoskeleton pathway
mmu04510
Focal adhesion pathway
mmu05412
Arrhythmogenic right ventricular cardiomyopathy (ARVC) pathway
mmu05410
Hypertrophic cardiomyopathy (HCM) pathway
mmu05414
Dilated cardiomyopathy pathway
mmu04145
Phagosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_22
Leptin pathway
REACTOME
REACT_111174
Cross-presentation of particulate exogenous antigens (phagosomes) pathway
REACT_13552
Integrin cell surface interactions pathway
REACT_150331
Molecules associated with elastic fibres pathway
REACT_150366
Elastic fibre formation pathway
REACT_20558
Smooth Muscle Contraction pathway
REACT_118779
Extracellular matrix organization pathway
REACT_163942
Syndecan interactions pathway
REACT_111119
Antigen processing-Cross presentation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_163906
ECM proteoglycans pathway
REACT_163874
Non-integrin membrane-ECM interactions pathway
REACT_17044
Muscle contraction pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
KEGG
hsa04810
Regulation of actin cytoskeleton pathway
hsa04512
ECM-receptor interaction pathway
hsa04510
Focal adhesion pathway
hsa05412
Arrhythmogenic right ventricular cardiomyopathy (ARVC) pathway
hsa05410
Hypertrophic cardiomyopathy (HCM) pathway
hsa05414
Dilated cardiomyopathy pathway
hsa04145
Phagosome pathway
INOH
INOH website
Integrin signaling pathway pathway
PID NCI
integrin_cs_pathway
Integrin family cell surface interactions
upa_upar_pathway
Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
fak_pathway
Signaling events mediated by focal adhesion kinase
smad2_3nuclearpathway
Regulation of nuclear SMAD2/3 signaling
integrin5_pathway
Beta5 beta6 beta7 and beta8 integrin cell surface interactions
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.6424
RefSeq NM_001145884 NM_010580
OMIM
CCDS CCDS28135 CCDS49835
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca