InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Vamp8

Summary

InnateDB Gene

IDBG-157267.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Vamp8

Gene Name

vesicle-associated membrane protein 8

Synonyms

AU041171; Edb; endobrevin

Species

Mus musculus

Ensembl Gene

ENSMUSG00000050732

Encoded Proteins

IDBP-157269

vesicle-associated membrane protein 8

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000118640:
This gene encodes an integral membrane protein that belongs to the synaptobrevin/vesicle-associated membrane protein subfamily of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs). The encoded protein is involved in the fusion of synaptic vesicles with the presynaptic membrane.[provided by RefSeq, Jun 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 6:72385223-72390703

Strand

Reverse strand

Band

Transcripts

ENSMUST00000059983	ENSMUSP00000059501
ENSMUST00000142613

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Experimentally validated
Total	11 [view]
Protein-Protein	10 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000149	SNARE binding
GO:0005484	SNAP receptor activity
GO:0005515	protein binding
GO:0019905	syntaxin binding

Biological Process

GO:0000046	autophagic vacuole fusion
GO:0006461	protein complex assembly
GO:0006887	exocytosis
GO:0006906	vesicle fusion
GO:0015031	protein transport
GO:0016192	vesicle-mediated transport
GO:0030100	regulation of endocytosis
GO:0035493	SNARE complex assembly
GO:0046718	viral entry into host cell
GO:0061025	membrane fusion

Cellular Component

GO:0005739	mitochondrion
GO:0005765	lysosomal membrane
GO:0005769	early endosome
GO:0009986	cell surface
GO:0016021	integral component of membrane
GO:0030141	secretory granule
GO:0031201	SNARE complex
GO:0031902	late endosome membrane
GO:0055037	recycling endosome
GO:0070062	extracellular vesicular exosome