Version 5.4
Mus musculus Gene: Ppp2r2c
Summary
InnateDB Gene IDBG-158563.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ppp2r2c
Gene Name protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000029120
Encoded Proteins
IDBP-158565
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000074211:
The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:36868513-36955078
Strand Forward strand
Band B3
Transcripts
ENSMUST00000031003 ENSMUSP00000031003
ENSMUST00000138124
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008601 protein phosphatase type 2A regulator activity
Biological Process
GO:0007165 signal transduction
GO:0050790 regulation of catalytic activity
Cellular Component
GO:0000159 protein phosphatase type 2A complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000074211
View Gene Order
ENSBTAG00000020598
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04530
Tight junction pathway
mmu03015
mRNA surveillance pathway pathway
mmu05160
Hepatitis C pathway
mmu05142
Chagas disease (American trypanosomiasis) pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04530
Tight junction pathway
hsa05142
Chagas disease (American trypanosomiasis) pathway
hsa03015
mRNA surveillance pathway pathway
hsa05160
Hepatitis C pathway
INOH
INOH website
Insulin receptor signaling pathway
INOH website
GPCR Dopamine D1like receptor signaling pathway pathway
PID NCI
Cross-References
SwissProt Q8BG02
TrEMBL
UniProt Splice Variant
Entrez Gene 269643
UniGene Mm.396868 Mm.41694
RefSeq NM_172994 XM_006503971 XM_006503972
OMIM
CCDS CCDS19244
HPRD
IMGT
MGI ID MGI:2442660
MGI Symbol Ppp2r2c
EMBL AK032023 AK049830 AY348866 BC059811
GenPept AAH59811 AAQ55226 BAC27654 BAC33942
RNA Seq Atlas 269643

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca