Mus musculus Gene: Pomt1
Summary
InnateDB Gene IDBG-159096.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pomt1
Gene Name protein-O-mannosyltransferase 1
Synonyms AI505244;
Species Mus musculus
Ensembl Gene ENSMUSG00000039254
Encoded Proteins
protein-O-mannosyltransferase 1
protein-O-mannosyltransferase 1
protein-O-mannosyltransferase 1
protein-O-mannosyltransferase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130714:
The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS) and limb-girdle muscular dystrophy type 2K (LGMD2K). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:32236590-32255005
Strand Forward strand
Band B
Transcripts
ENSMUST00000036473 ENSMUSP00000038722
ENSMUST00000126784
ENSMUST00000154684
ENSMUST00000129163
ENSMUST00000146485 ENSMUSP00000116117
ENSMUST00000123740 ENSMUSP00000116543
ENSMUST00000132516 ENSMUSP00000118382
ENSMUST00000132853
ENSMUST00000138000
ENSMUST00000151598
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000030 mannosyltransferase activity
GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006493 protein O-linked glycosylation
GO:0030198 extracellular matrix organization
GO:0035269 protein O-linked mannosylation
GO:0097502 mannosylation
Cellular Component
GO:0001669 acrosomal vesicle
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016529 sarcoplasmic reticulum
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Other types of O-glycan biosynthesis pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Other types of O-glycan biosynthesis pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_145145 XM_006498469 XM_006498473
OMIM
CCDS CCDS15908
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas