Homo sapiens Gene: LSM7
Summary
InnateDB Gene IDBG-15927.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LSM7
Gene Name LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000130332
Encoded Proteins
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Apr 2004]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:2321517-2328620
Strand Reverse strand
Band p13.3
Transcripts
ENST00000252622 ENSP00000252622
ENST00000589532
ENST00000585395 ENSP00000466556
ENST00000591745
ENST00000587502 ENSP00000485007
ENST00000591515
ENST00000585409 ENSP00000467145
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 46 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 46 [view]
Protein-Protein 46 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017070 U6 snRNA binding
Biological Process
GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0010467 gene expression
GO:0016070 RNA metabolic process
GO:0016071 mRNA metabolic process
GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
Cellular Component
GO:0005681 spliceosomal complex
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
mRNA decay by 5' to 3' exoribonuclease pathway
Deadenylation-dependent mRNA decay pathway
Gene Expression pathway
KEGG
RNA degradation pathway
Spliceosome pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.683921
RefSeq NM_016199
HUGO
OMIM
CCDS CCDS45907
HPRD 06287
IMGT
EMBL
GenPept
RNA Seq Atlas