InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Dok1

Summary

InnateDB Gene

IDBG-159342.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dok1

Gene Name

docking protein 1

Synonyms

AW557123; p62DOK

Species

Mus musculus

Ensembl Gene

ENSMUSG00000068335

Encoded Proteins

IDBP-159344

docking protein 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115325:
The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 6:83030934-83033471

Strand

Reverse strand

Band

Transcripts

ENSMUST00000089651	ENSMUSP00000087079
ENSMUST00000149918

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 42 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.

Experimentally validated
Total	42 [view]
Protein-Protein	42 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	30 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005057	receptor signaling protein activity
GO:0005158	insulin receptor binding
GO:0005515	protein binding

Biological Process

GO:0000165	MAPK cascade
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007265	Ras protein signal transduction
GO:0035556	intracellular signal transduction