InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Cct3

Summary

InnateDB Gene

IDBG-160136.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cct3

Gene Name

chaperonin containing Tcp1, subunit 3 (gamma)

Synonyms

AL024092; Cctg; Tcp1-rs3; TriC-P5

Species

Mus musculus

Ensembl Gene

ENSMUSG00000001416

Encoded Proteins

IDBP-160138

chaperonin containing Tcp1, subunit 3 (gamma)

IDBP-620594

chaperonin containing Tcp1, subunit 3 (gamma)

IDBP-620595

chaperonin containing Tcp1, subunit 3 (gamma)

IDBP-620596

chaperonin containing Tcp1, subunit 3 (gamma)

IDBP-620597

chaperonin containing Tcp1, subunit 3 (gamma)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163468:
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8. [provided by RefSeq, Aug 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:88297116-88321767

Strand

Forward strand

Band

Transcripts

ENSMUST00000001452	ENSMUSP00000001452
ENSMUST00000167000
ENSMUST00000164783
ENSMUST00000167718
ENSMUST00000164166	ENSMUSP00000126109
ENSMUST00000168062	ENSMUSP00000131113
ENSMUST00000163735	ENSMUSP00000130616
ENSMUST00000164122
ENSMUST00000168971	ENSMUSP00000131250

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 93 interaction(s) predicted by orthology.

Experimentally validated
Total	22 [view]
Protein-Protein	22 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	93 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0044822	poly(A) RNA binding
GO:0051082	unfolded protein binding

Biological Process

GO:0006457	protein folding
GO:0007339	binding of sperm to zona pellucida
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0002199	zona pellucida receptor complex
GO:0005737	cytoplasm
GO:0005832	chaperonin-containing T-complex
GO:0005874	microtubule
GO:0005886	plasma membrane
GO:0044297	cell body
GO:0070062	extracellular vesicular exosome