Mus musculus Gene: Blvrb
Summary
InnateDB Gene IDBG-161057.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Blvrb
Gene Name biliverdin reductase B (flavin reductase (NADPH))
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000040466
Encoded Proteins
biliverdin reductase B (flavin reductase (NADPH))
biliverdin reductase B (flavin reductase (NADPH))
biliverdin reductase B (flavin reductase (NADPH))
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000090013:
The final step in heme metabolism in mammals is catalyzed by the cytosolic biliverdin reductase enzymes A and B (EC 1.3.1.24).[supplied by OMIM, Jul 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:27447978-27466144
Strand Forward strand
Band A3
Transcripts
ENSMUST00000037399 ENSMUSP00000043092
ENSMUST00000108358 ENSMUSP00000103995
ENSMUST00000108357 ENSMUSP00000103994
ENSMUST00000133750
ENSMUST00000153644
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity
GO:0004074 biliverdin reductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0042602 riboflavin reductase (NADPH) activity
GO:0050662 coenzyme binding
Biological Process
GO:0006694 steroid biosynthetic process
GO:0042167 heme catabolic process
GO:0044237 cellular metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
Metabolism pathway
Heme degradation pathway
Metabolism of porphyrins pathway
KEGG
Riboflavin metabolism pathway
Porphyrin and chlorophyll metabolism pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Heme degradation pathway
Metabolism of porphyrins pathway
Metabolism pathway
Heme degradation pathway
Metabolism of porphyrins pathway
Metabolism pathway
KEGG
Riboflavin metabolism pathway
Porphyrin and chlorophyll metabolism pathway
INOH
PID BIOCARTA
Il-10 anti-inflammatory signaling pathway [Biocarta view]
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001290525 NM_144923 XM_006539861
OMIM
CCDS CCDS39848 CCDS71922
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas