Mus musculus Gene: Mrpl52
Summary
InnateDB Gene IDBG-161133.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mrpl52
Gene Name mitochondrial ribosomal protein L52
Synonyms 1110047B07Rik;
Species Mus musculus
Ensembl Gene ENSMUSG00000010406
Encoded Proteins
mitochondrial ribosomal protein L52
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000172590:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which has no bacterial homolog. Multiple transcript variants encoding different protein isoforms were identified through sequence analysis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:54426909-54429750
Strand Forward strand
Band C2
Transcripts
ENSMUST00000010550 ENSMUSP00000010550
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0008150 biological_process
Cellular Component
GO:0005739 mitochondrion
GO:0005762 mitochondrial large ribosomal subunit
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Mitochondrial translation pathway
Organelle biogenesis and maintenance pathway
Mitochondrial translation elongation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Organelle biogenesis and maintenance pathway
Mitochondrial translation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
Mitochondrial translation elongation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation elongation pathway
Mitochondrial translation pathway
Mitochondrial translation termination pathway
Organelle biogenesis and maintenance pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q9D0Y8
TrEMBL
UniProt Splice Variant
Entrez Gene 68836
UniGene
RefSeq NM_026851
OMIM
CCDS CCDS27088
HPRD
IMGT
MGI ID MGI:1916086
MGI Symbol Mrpl52
EMBL AK004194 AK150806 AK151615 AK152876 AK164629 BC028522 BC060043
GenPept AAH28522 AAH60043 BAB23216 BAE29869 BAE30552 BAE31561 BAE37850
RNA Seq Atlas 68836